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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC24A2 All Species: 24.24
Human Site: S460 Identified Species: 44.44
UniProt: Q9UI40 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UI40 NP_065077.1 661 73664 S460 E E E D Q P L S L A W P S E T
Chimpanzee Pan troglodytes XP_528551 661 73638 S460 E E E D Q P L S L A W P S E T
Rhesus Macaque Macaca mulatta XP_001108751 661 73840 S460 D E E D Q P L S L A W P S E T
Dog Lupus familis XP_852036 664 74187 S463 D E E D Q P L S L A W P S N P
Cat Felis silvestris
Mouse Mus musculus Q8CGQ8 605 66848 W414 K A K W V F T W P L I F L L C
Rat Rattus norvegicus O54701 670 74638 S469 E D D D Q P L S L S W P S N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514353 346 38802 L156 D E F F V P S L T V I T E K L
Chicken Gallus gallus Q9IAL7 651 72677 S450 E D E D Q P L S L A W P D T P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q49SH1 513 56764 V322 D L K R I L W V L S L P V S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U6A0 888 95868 S690 E D E P E P L S M A W P D T A
Honey Bee Apis mellifera XP_396230 658 71609 D460 D D P P E A L D M G W P S S A
Nematode Worm Caenorhab. elegans NP_001040663 596 66359 V406 Y V L L A P V V I P M W V T I
Sea Urchin Strong. purpuratus XP_787540 651 70927 D450 M E V E E P L D I S W P K G W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.1 93.2 N.A. 35.2 88.6 N.A. 39.3 77 N.A. 31 N.A. 38.9 46.9 42.2 39.4
Protein Similarity: 100 99.8 98.6 95.3 N.A. 53.5 93.4 N.A. 44.9 86.8 N.A. 50.3 N.A. 53.2 61.2 60.3 53.8
P-Site Identity: 100 100 93.3 80 N.A. 0 73.3 N.A. 13.3 73.3 N.A. 20 N.A. 53.3 26.6 6.6 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 13.3 93.3 N.A. 26.6 80 N.A. 40 N.A. 73.3 53.3 20 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 8 0 0 0 47 0 0 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 39 31 8 47 0 0 0 16 0 0 0 0 16 0 0 % D
% Glu: 39 47 47 8 24 0 0 0 0 0 0 0 8 24 0 % E
% Phe: 0 0 8 8 0 8 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 16 0 16 0 0 0 8 % I
% Lys: 8 0 16 0 0 0 0 0 0 0 0 0 8 8 0 % K
% Leu: 0 8 8 8 0 8 70 8 54 8 8 0 8 8 8 % L
% Met: 8 0 0 0 0 0 0 0 16 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % N
% Pro: 0 0 8 16 0 77 0 0 8 8 0 77 0 0 16 % P
% Gln: 0 0 0 0 47 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 8 54 0 24 0 0 47 16 0 % S
% Thr: 0 0 0 0 0 0 8 0 8 0 0 8 0 24 39 % T
% Val: 0 8 8 0 16 0 8 16 0 8 0 0 16 0 0 % V
% Trp: 0 0 0 8 0 0 8 8 0 0 70 8 0 0 8 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _